Nonylphenol (NP) and nonylphenol ethoxylates (NPEs) are produced in large volumes, with uses that lead to widespread release to the aquatic environment. NP is persistent in the aquatic environment, moderately bioaccumulative, and extremely toxic to aquatic organisms. NP’s main use is in the manufacture of NPEs.

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Get the Facts: NPEs (nonylphenol ethoxylates) · Hormone (endocrine) disruption · Extreme aquatic toxicity · Skin and eye irritation · Reproductive harm · Birth defects 

Nonylphenol (NP) is the commercially most important member of the group of alkyl phenols. The term “nonylphenol” represents a large num-ber of isomeric compounds, varying in the point of attachment of the nonyl group to the phenol molecule, and in the degree of branching in the nonyl moiety. Commercially produced nonylphenols are predominantly In sewage treatment plants, nonylphenol ethoxylate degrades into nonylphenol, which is found in river water and sediments as well as soil and groundwater. Nonylphenol photodegrades in sunlight, but its half-life in sediment is estimated to be more than 60 years. We simulated the formation of halogenated by‐products of biodegradation products of a nonionic surfactant, nonylphenol ethoxylate (NPE), and evaluated the toxicity of these by‐products.

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ence of nonylphenol ethoxylate surfactants and their pri- 2018-06-20 · The U.S. Environmental Protection Agency (EPA) expanded on June 12, 2018, the list of chemicals subject to reporting under the Emergency Planning and Community Right-to-Know Act (EPCRA) Toxics Release Inventory (TRI). The list now includes a category containing 13 nonylphenol ethoxylates (NPE). Nonylphenol and short-chain nonylphenol ethoxylates such as NP 2 EO are present in aquatic environment as wastewater contaminants, and their toxic effects on aquatic species have been reported. Apoptosis has been shown to be induced by serum deprivation or copper treatment. Nonylphenol and its ethoxylates (NP and NPEs) have been used for more than 40 years as detergents, emulsifiers, wetting agents and dispersing agents.

One of these environmental pollutants is nonylphenol ethoxylate (NP-9), also known as Tergitol, and its degradation product, nonylphenol (NP). The objective of this work was to determine the toxicity of NP and NP-9 in Caenorhabditis elegans.

Nonylphenol ethoxylates in imported textiles iii Abstract Nonylphenol is a priority hazardous substance under the Water Framework Directive (WFD) due to its potential impact upon the aquatic environment. Water quality monitoring continues to detect nonylphenol (NP) and nonylphenol ethoxylate (NPE) in waterways across the UK.

The mostly used APEs, nonylphenol ethoxylates (NPEs) has an alkyl chain (C9H19, usually branched) and a chain of 9-10 ethoxylate groups (see Fig.1) [9]. With decreasing length of the ethoxylate chain, bioaccumulation and toxicity of APEs increases [10]. Nonylphenol (NP) is the commercially most important member of the group of alkyl phenols. The term “nonylphenol” represents a large num-ber of isomeric compounds, varying in the point of attachment of the nonyl group to the phenol molecule, and in the degree of branching in the nonyl moiety.

Nonylphenol ethoxylate toxicity

B E Fatty alcohol ethoxylates nonylphenol- or risk => A = Allergy, C = Cancer, T = Toxic, E = Environmentally hazardous, N = Neurotoxic,.

Nonylphenol ethoxylates in imported textiles iii Abstract Nonylphenol is a priority hazardous substance under the Water Framework Directive (WFD) due to its potential impact upon the aquatic environment. Water quality monitoring continues to detect nonylphenol (NP) and nonylphenol ethoxylate (NPE) in waterways across the UK. NPEs are degraded to shorter chain nonylphenol ethoxylates as well as shorter nonylphenol ethoxycarboxylates under aerobic condition, before being biodegraded to nonylphenol. Shorter ethoxylate chain alkylphenols have greater toxicity than longer ones. CCME describes Toxic Equivalent Factors from Environment Canada for NPnEO (1≤n≤8) Nonylphenol is toxic to aquatic organisms demonstrated, in part, through recent national criteria established by the EPA (AWQC– Nonylphenol 2007( EPA822R05005)). The need to develop national criteria was based both on concerns of NP toxicity and its presence in surface waters throughout the nation. The We simulated the formation of halogenated by-products of biodegradation products of a nonionic surfactant, nonylphenol ethoxylate (NPE), and evaluated the toxicity of these by-products.

Nonylphenol ethoxylate toxicity

Apoptosis has been shown to be induced by serum deprivation or copper treatment. As per the Government of Canada (2007), “Nonylphenol ethoxylates (NPEs) are a class of the broader group of compounds known as alkylphenol ethoxylates (APEs).
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2 Hazard statement: H315: Causes skin irritation.

H302 Harmful if swallowed. H315 Causes skin irritation. H318 Causes serious eye damage.
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tion of NPEs occurs through the loss of ethoxylate (EO) groups, resulting in compounds that are more toxic, estrogenic, and environmentally persistent than the parent compounds (Environment Canada 2000). Primary biodeg-radation of NPEs in aquatic systems is fast, but the resul-tant products, nonylphenol monoethoxylate (NP1EO),

Nonyl-phenol ethoxylates have much narrower homologue distributions than alcohol ethoxylates (ICI datasheet for Synperonic NP surfactants). 880 million pounds (4 mio metric tonnes) of alkyl phenol ethoxylates are used annually throughout the world. 80-85% are sold as nonylphenol ethoxylate (NPE), over 15% as octylphenol ethoxylate, and 1% each as Toxic substances list: nonylphenol and its ethoxylates.


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alkyl chain, and a water soluble chain of 1-100 ethoxylate groups (1EO-100EO) [7]. The mostly used APEs, nonylphenol ethoxylates (NPEs) has an alkyl chain (C9H19, usually branched) and a chain of 9-10 ethoxylate groups (see Fig.1) [9]. With decreasing length of the ethoxylate chain, bioaccumulation and toxicity of APEs increases [10].

§§1691 through 1699-B]. The goal of the law as  23 Mar 2018 NP and NPEs are toxic and estrogenic. The term “nonylphenol ethoxylates” refers to a large group of chemicals that vary in chemical structure  26 Jan 2018 Abstract: An experiment was carried out to explore acute and chronic toxicity of nonylphenol ethoxylates (NP40EO) to Daphnia magna and the  (1-2, 19) Based on this data, nearly 77 million pounds of NPE-based cleaning agents entered U.S. waterways in. 2004. Toxicity of Nonylphenol.

26 Jan 2018 Abstract: An experiment was carried out to explore acute and chronic toxicity of nonylphenol ethoxylates (NP40EO) to Daphnia magna and the 

According to the classification provided by companies to ECHA in CLP notifications this substance is toxic to aquatic life with long lasting effects, causes serious eye damage, is harmful if swallowed and causes skin irritation. their toxicity to the freshwater species Pimephales promelas (fathead minnow) and Ceriodaphnia dubia. Acute toxicity tests using nonylphenol (NP), nonylphenol monoethoxylate (NP1EO), and nonylphenol diethoxylate (NP2EO) were conducted using the single chemicals and as binary and tertiary mixtures. These compounds frequently Acute toxicity - oral Reason for no classification: data conclusive but not sufficient for classification Acute toxicity - dermal Reason for no classification: data lacking Acute toxicity - inhalation Reason for no classification: data lacking Skin corrosion / irritation Hazard category: Skin Irrit. 2 Hazard statement: H315: Causes skin irritation.

toxicity tests were collected from the littoral area of Sancti Petri (Gulf of Cadiz, southwest of Iberian Peninsula). Main physico-chemical and biological characteristics of the sea water used are summarized in Table I. Assessment of the Biodegradability and Ecotoxicty of a Nonylphenol Ethoxylate Surfactant in Littoral Waters Among the most used chemicals in the world are nonionic surfactants. One of these environmental pollutants is nonylphenol ethoxylate (NP-9), also known as Tergitol, and its degradation product, nonylphenol (NP).